How To Get Rid Of Liver Flukes Naturally

You will find how to get rid of liver flukes in humans naturally in this article.

What are liver flukes?

Liver flukes belong to a group of parasitic flatworms known as trematodes3,4.

These parasites live principally in the liver of various mammals, including humans4.

They also colonize the bile ducts, gallbladder, and pancreas of their host4,5 .

Liver flukes affect millions of people worldwide, causing severe health problems1.

Historically, these parasites have been overlooked as far as human infections are concerned1.

However, liver fluke infection is now considered a neglected disease1,2.

Are there different types of liver flukes?

There are two families of human liver flukes1,6:

Fasciolidae, which comprise:

  • Fasciola hepatica
  • Fasciola gigantica

Opisthorchiidae, which include:

  • Clonorchis sinensis
  • Opisthorchis viverrini
  • Opisthorchis felineus

What damage do liver flukes do?

Liver flukes can mechanically obstruct your bile ducts, causing chronic inflammation (cholangitis)2,7.

Bile ducts obstructed (blocked) from liver flukes.

These parasites are classified as Type 1 carcinogens, as infection can lead to bile duct cancer (cholangiocarcinoma)1,2,8,9.

Furthermore, chronic bile duct obstruction may also lead to pancreatitis5,7,9,10.     

Related: Do Liver Flukes Cause Cancer?

What are the symptoms of liver fluke infection?

The main symptoms of liver fluke disease are chronic fatigue and abdominal complaints2.

Nevertheless, these parasites can induce a variety of other symptoms in humans.


What is the treatment for liver flukes?

Is there a vaccine for liver flukes?

There is no vaccine against liver flukes available for humans9,11.

What medicine kills liver flukes?

The classic treatment for liver flukes consists in taking an anthelmintic drug.

An anthelmintic drug is a medicine that expels parasitic worms from your body by either stunning or killing them12,13.

Anthelmintic drugs for the treatment of liver flukes in humans include:

Disadvantages of anthelmintic drugs

The downsides of anthelmintic drugs are that:

  1. Praziquantel7,9,10,14,15,21,22, albendazole9,21, and mebendazole9 are ineffective against Fasciola species.
  2. Praziquantel is also ineffective against the juvenile form of Opisthorchis viverrini23.
  3. Liver flukes show resistance to praziquantel18, triclabendazole1,21,24 and albendazole1,25
  4. These drugs can cause moderate or serious adverse effects and toxicity15,20,26.

Liver flukes and heavy metals

Studies have shown that heavy metals bio-accumulate in liver flukes27.

Furthermore, levels of heavy metals found in liver flukes are higher than in their hosts27,28.

Benefits of a heavy metal cleanse

Natural remedies that remove heavy metals (such as cadmium, thallium, and arsenic) from the human body have anti-liver fluke properties.

The possible underlying mechanism is that once freed from these heavy metals, the host’s immune system is more effective.

High concentrations of heavy metals have, namely, adverse effects on the immune system28,30.

As such, the proliferation of parasites is likely due to an impaired host immune response in polluted conditions.

Related: 10 Best Heavy Metal Detox Supplements

How to get rid of liver flukes naturally in humans

Some herbal medicines, foods, and nutritional supplements have shown anti-liver flukes properties in studies.

The benefit of these natural remedies is that they don’t cause any side effects and, as such, can be taken long-term.

If you wonder how to get rid of liver flukes naturally in humans, here is a list of the best remedies to do a cleanse:

1. Omega-3 fatty acids

Omega-3 fatty acids are among the strongest liver fluke killer remedies.

They, namely, increase glutathione levels31.

Glutathione, in turn, helps your body to get rid of heavy metals32.

Dietary supplements and foods rich in omega-3 fatty acids include:

Flaxseed oil

Flaxseed oil is an edible oil obtained by pressing flax seeds.

This oil is high in omega-3 fatty acids essential in the human diet33,34.

Furthermore, flaxseed oil removes heavy metals from your body.

Studies have shown that dietary supplementation with flaxseed oil reduces the number of Fasciola hepatica worms and eggs thanks to its omega-3 fatty acids content35.

This is because these fatty acids boost your immune response and target pathogens directly35.

Related: 20 Health Benefits Of Flaxseed Oil And Its Side Effects

Spinach juice

Spinach leaves, like other green leafy vegetables, are a good source of alpha-linolenic acid36.

Just like flaxseed oil, spinach juice has anti-fascioliasis properties thanks to its high omega-3 fatty acids content.

Moringa powder

Moringa oleifera is a fast-growing, small tree native to the Indian subcontinent37.

Studies have shown that moringa seeds and leaves reduce the number of Fasciola hepatica worms and eggs38,39,40.

Moringa seeds41 and leaves41,42 are high in omega-3 fatty acids.

Moreover, the anti-fascioliasis effects of moringa might also be attributed to tannins, flavonoids, phenolic acids, and saponins38,39,40.

2. Methyl donors

The methylation cycle is a process in your body that, among others, neutralizes heavy metals via the production of glutathione43,44.

Furthermore, methyl donors are substances that can transfer a methyl group.

Methyl donors and co-factors of the methylation cycle need to be present in sufficient amounts to keep the cycle running.

Hence methyl donors and co-factors of the methylation cycle have anti-liver fluke properties.

They include45,46,70,71

  • Methionine
  • Folate (not toxic folic acid)
  • Betaine/choline
  • Vitamin B2, B3, and B6
  • Zinc

3. Vitamins

The use of natural antioxidants, including minerals and vitamins as anthelmintic agents has recently begun to be studied47.

Some of them show good anti-parasitic potential.

The possible underlying mechanism is that liver flukes need high levels of vitamins to survive and proliferate48.

As a result, they deplete the host’s vitamin A49, C50, and E51, diminishing its immune response.

As such, dietary supplementation with high doses of these vitamins restores the host’s defense mechanisms and its ability to get rid of liver flukes.

Vitamin E

A study has shown that vitamin E, α-tocopherol, reduces the number of Fasciola hepatica worms35.

Also, it decreases bile duct cancer (cholangiocarcinoma) caused by Opisthorchis viverrini liver flukes51.

Fresh spinach juice is a rich source of natural vitamin E68,69.

Vitamin C

Research revealed that vitamin C kills liver fluke-induced bile duct cancer cells52.

Consequently, high doses of vitamin C can help you get rid of liver fluke disease.

4. Goldenseal (berberine)

Goldenseal, which scientific name is Hydrastis canadensis, is a perennial plant native to North America.

It is a rich source of isoquinoline alkaloids, including berberine and hydrastine.

Goldenseal (Hydrastis canadensis) for the treatment of liver flukes.

A study has shown that berberine has protective effects against blood flukes, another type of flukes53.

Thanks to its antioxidant properties, it increases glutathione levels53.

The herbal medicine goldenseal or its extract berberine are both effective for the treatment of liver flukes.

5. Artemisinin

Artemisia annua and Artemisia ludoviciana are two flowering plants that belong to the Asteraceae family54,55.

A study has shown that Artemisia annua kills Fasciola hepatica liver flukes56.

It also helps to cleanse intestinal and blood flukes56.

Artemisia annua to cleanse liver flukes.

Furthermore, research revealed that Artemisia ludoviciana (mexicana) has fasciolicidal effects57,58.

The active component of both plants is artemisinin56,57.

As a consequence, artemisinin can be used to get rid of liver flukes naturally.

Related: 7 Foods To Avoid When You’re Infected With Parasites

6. Quercetin

Natural antioxidants found in plants such as polyphenols and terpenes have anti-liver fluke effects59.

Quercetin is a plant flavonoid found in fruits and vegetables60.

Research indicates that quercetin has anthelmintic activity against Opisthorchis felineus47.

Also, leaves of the tropical plant bitter melon (momordica charantia) have anti-helminthic activity against Fasciola hepatica eggs thanks to their quercetin content61.

Bitter melon (Momordica charantia) to get rid of liver flukes.

The herbal medicine bitter melon or quercetin alone can be used for the treatment of liver fluke disease.

Related: Top 13 Foods That Kill Parasites In Humans

7. Turmeric root

Turmeric (Curcuma longa) is a flowering plant of the Zingiberaceae family62,63.

The main active substances of turmeric root are curcumin and turmerone63,64.

Studies have shown that curcumin eliminates Fasciola giganta65.

Curcumin also prevents and decreases Opisthorchis viverrini-induced bile duct cancer66,67.

Related: 17 Health Benefits Of Turmeric And Curcumin


  • Choose one of the supplements mentioned above.
  • Take the smallest possible dosage.
  • Wait a few days to see how your body reacts.
  • Gradually, increase the amount.
  • Later, switch to another supplement.
  • Regularly take a break from the treatment to allow your body to evacuate the dead flukes and their toxins.

Related: Pumpkin Seeds For Intestinal Parasites

Liver flukes treatment and side effects

Dead liver flukes tend to remain blocked in your digestive tract if you don’t eat enough fiber.

Good sources of fiber are: plums/prunes or psyllium husk.

Dietary supplements for liver fluke infection may cause a Herxheimer reaction.

Here Is How To Get Rid Of A Herxheimer Reaction Naturally.

Summary: How to get rid of liver flukes naturally

Anthelmintic drugs such as praziquantel, albendazole, mebendazole, and triclabendazole have disadvantages.

Their major drawbacks are inefficacy, resistance, side effects, and toxicity.

If you wonder how to get rid of liver flukes naturally in humans, several remedies can help you.

They work by boosting your immune system or attacking the parasites directly.

Here are the best natural remedies for the treatment of liver flukes in humans:

  1. Omega-3 fatty acids
  2. Methyl donors
  3. Vitamin E and C
  4. Artemisinin
  5. Quercetin
  6. Goldenseal (berberine)
  7. Turmeric

Related: An Easy Way To Know If You Have Liver Flukes

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